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无心跳供体肺原位降温保护系统的研究
彭富裕1, 胥义1, 赵晓刚2, 刘道平1, 钟彦骞1
0
(1.上海理工大学;2.上海市肺科医院)
摘要:
针对无心跳供体肺原位冷却保护的要求,分别借助支气管和胸腔途径,研发了由保护气体冷却和保护液体冷却两种手段相结合的快速降温保护系统。实验结果表明:气管通气冷却只对支气管及其附近的区域有较好的降温效果,而对气管末梢及肺表面区域的降温效果很差;胸腔循?环保护液体冷却对肺表面和内部都有不错的冷却效果,但这种方式却有可能造成肺实质的机械损伤。
关键词:  热工学  半导体制冷  快速降温  原位冷却保护  无心跳供体
DOI:
投稿时间:2011-09-06    
基金项目:国家自然科学基金(50906056)资助项目。
Research of a Cooling System for Preserving Non-Heart-Beating Donor Lungs in Situ
Peng Fuyu1, Xu Yi1, Zhao Xiaogang2, Liu Daoping1, Zhong Yanqian1
(1.University of Shanghai for Science and Technology;2.Shanghai Pulmonary Hospital)
Abstract:
For the requirements of lung preservation with low temperature in situ, a rapid cooling and preservative system was developed. By the way of bronchus and thorax, the temperature of donor lung would be reduced respectively with cooling gas and cooling water. The experimental results showed that the cooling effect would be better in the areas closer to the entrance of the trachea with cooling gas and there was nearly no effect in the end of bronchus. With cooling fluid, the cooling effect was satisfied both in the surface and internal area except some potential mechanical damage for lung tissue.
Key words:  pyrology  semiconductor refrigeration  rapid cooling  cooling preservation in situ  non-heart-beating donors

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