| 摘要: |
| Cryotop 冷冻技术是目前卵母细胞玻璃化保存较为有效的方法，它以操作简单、获得的冷冻速率较高而得到广泛应用。近年来研究者们采用数值计算的方式对其传热性能进行研究，但计算中涉及的模型冷冻过程中的对流换热系数却没有有依据的取值范围。文章以三种载板厚度的Cryotop模型为研究对象，采用超快速测温装置对水滴冷冻过程进行温度测量，同时用模拟计算的方法得到不同对流换热系数下水滴冷冻过程的冷却速率，将两者进行比较，找出与实际测温所得结果相吻合的模拟实验中所需要的对流换热系数取值范围。结果表明：三种不同载板厚度的Cryotop模型在模拟计算中对流换热系数的取定范围为6000~8000 W/(m2.K)。 |
| 关键词: 热工学 Cryotop 对流换热系数 超快速测温 数值模拟 |
| DOI： |
| 投稿时间：2011-10-12
|
| 基金项目:国家自然科学基金（50906057）资助项目。 |
|
| The Analysis of Heat Transfer Coefficient in Freezing Process of Cryotop |
| Wang Haisong,Zhou Xinli,Li Weijie |
| (Institute of Biothermal Technology, University of Shanghai for Science and Technology) |
| Abstract: |
| The Cryotop is an efficient vitrification method for cryopreservation of oocytes. It has been widely used owing to its simple operation and high freezing rates. Recently, its heat transfer performance is frequently studied by the way of numerical simulation. However, the range of heat transfer coefficient in the simulation is uncertain. Three kinds of Cryotop models with different board thickness were studied. The cooling rates of water droplets in freezing process of Cryotop were measured by ultra-fast measurement and calculated by numerical simulation. Comparing the results obtained by two methods, the range of the heat transfer coefficient which was needed in the numerical simulation of Cryotop was found. The result showed that the range of the heat transfer coefficient is 6000~8000 W/(m2.K). |
| Key words: pyrology cryotop heat transfer coefficient ultra-fast temperature measurement numerical simulation |
