| 摘要: |
| 本文以小鼠作为实验对象，研究了离体小鼠皮肤组织加热过程中热物性及力学参数的变化，讨论了温度及水分等因素的影响规律。结果表明：在加热过程（37~47 ℃）中，皮肤组织应力应变曲线近似为线性，弹性模量与温度相关，且随着温度的升高而逐渐减小，泊松比变化与之相似；加热初期（37~45 ℃），组织含水率减少不明显，热导率随温度的升高而缓慢增加；随着温度的升高与时间的推移，组织逐渐失水，含水率对热导率的影响高于温度对其的影响，45 ℃时热导率开始急剧下降，在45~47 ℃，热导率值下降了5.4%，比热容变化与之相似。 |
| 关键词: 皮肤组织 热物性 力学特性 含水率 |
| DOI： |
| 投稿时间：2018-10-18 修订日期：2018-11-29
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| 基金项目:国家自然科学基金青年项目（No.51506151）和天津市自然科学青年基金项目（16JCQNJC14000）资助。。 |
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| Study on Changes of Thermophysical Properties and Mechanical Parameters of Rat Skin during Heating Process |
| Zhang Xilong,Zhu Kai,Wang Yabo,Song Ting |
| (Key Laboratory of Refrigeration Technology of Tianjin, Tianjin University of Commerce) |
| Abstract: |
| Current research on the properties of skin is far from perfect. This poses certain difficulties for hyperthermia and related clinical research. Rats were used as experimental subjects to study the changes of thermophysical properties and mechanical parameters during heating and the influence of temperature and moisture was discussed. The results suggested that the stress and strain curves of the skin tissue were approximately linear during heating (37–47 ℃). The elastic modulus was related to the temperature and decreased gradually when the temperature increased. As the temperature increased, Poisson's ratio for the tissue changed similarly. In addition, during the initial stage of heating (37-45 ℃), the water content of the tissue was not significantly reduced. The thermal conductivity increased very slowly with the increasing temperature and remained almost unchanged. However, as the temperature and time increased, the tissue began to lose water. The effect of the water content on the thermal conductivity was higher than the effect of the temperature. When the temperature reached 45 ℃, the thermal conductivity began to drop sharply;from 45 ℃ to 47 ℃, the thermal conductivity value decreased by 5.4% and the specific heat capacity changed similarly. |
| Key words: skin tissue thermophysical property biomechanics moisture content |
